Publications
Peer Reviewed Articles
Scarborough, J.A., Weaver, D., & Scott, J. (2025). Gene Signatures and Oncology Treatment Implications. Hematology/Oncology Clinics, 39(2), 295-307.
Scarborough, J.A., Eschrich, S.A., Torres-Roca, J. et al. Exploiting convergent phenotypes to derive a pan-cancer cisplatin response gene expression signature. npj Precis. Onc. 7, 38 (2023). https://doi.org/10.1038/s41698-023-00375-y
Lin-Rahardja, K., Weaver, D. T., Scarborough, J. A., & Scott, J. G. (2023). Evolution-Informed Strategies for Combating Drug Resistance in Cancer. International Journal of Molecular Sciences, 24(7), 6738.
Asha, W., Koro, S., Mayo, Z., Yang, K., Halima, A., Scott, J., Scarborough, J.A. ... & Shah, C. (2023). Stereotactic Body Radiation Therapy for Sarcoma Pulmonary Metastases. American Journal of Clinical Oncology, 10-1097.
Scarborough, J. A., & Scott, J. G. (2022, January). Translation of Precision Medicine Research Into Biomarker-Informed Care in Radiation Oncology. In Seminars in Radiation Oncology (Vol. 32, No. 1, pp. 42-53). WB Saunders.
Ruthberg, J. S., Kocharyan, A., Farrokhian, N., Stahl, M. C., Hicks, K., Scarborough, J.A., ... & Otteson, T. (2022). Hearing loss patterns in enlarged vestibular aqueduct syndrome: Do fluctuations have clinical significance?. International Journal of Pediatric Otorhinolaryngology, 111072.
Weaver, D. T., Pishas, K. I., Williamson, D., Scarborough, J.A., Lessnick, S. L., Dhawan, A., & Scott, J. G. (2021). Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma. PLoS computational biology, 17(10), e1008755.
Scott, J. G., Sedor, G., Ellsworth, P., Scarborough, J. A., Ahmed, K. A., Oliver, D. E., ... & Torres-Roca, J. F. (2021). Pan-cancer prediction of radiotherapy benefit using genomic-adjusted radiation dose (GARD): a cohort-based pooled analysis. The Lancet Oncology, 22(9), 1221-1229.
Scott, J. G., Sedor, G., Scarborough, J. A., Kattan, M. W., & Torres-Roca, J. F. (2021). Radiotherapy with genomic-adjusted radiation dose–Authors' reply. The Lancet Oncology, 22(11), e470-e471.
Weaver D.T., McElvany B.D., Gopalakrishnan V, Card K.J., Crozier D, Dhawan A, Dinh M.N., Dolson E, Farrokhian N, Hitomi M, Ho E, Jagdish T, King E.S., Cadnum J.L., Donskey C.J., Krishnan N, Kuzmin G, Li J, Maltas J, Mo J, Pelesko J, Scarborough J.A., Sedor G, Tian E, An G.C., Diehl S.A., Scott J.G. UV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemic. PLoS One. 2021;16(7):e0241734. doi: 10.1371/journal.pone.0241734. eCollection 2021. PubMed PMID: 34310599; PubMed Central PMCID: PMC8312969.
Robinson N.J., Miyagi M, Scarborough J.A., Scott J.G., Taylor D.J., Schiemann W.P.. SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling. Sci Signal. 2021 Jun 29;14(689). doi: 10.1126/scisignal.abe9613. PubMed PMID: 34187905; PubMed Central PMCID: PMC8353884.
Scarborough J.A., Tom M.C., Kattan M.W, Scott J.G.. Revisiting a Null Hypothesis: Exploring the Parameters of Oligometastasis Treatment. Int J Radiat Oncol Biol Phys. 2021 Jun 1;110(2):371-381. doi: 10.1016/j.ijrobp.2020.12.044. Epub 2021 Jan 21. PubMed PMID: 33484786; PubMed Central PMCID: PMC8122026.
Scarborough J.A., McClure E., Anderson P., Dhawan A., Durmaz A., Lessnick, S.L., Hitomi, M., Scott, J.G., Identifying States of Collateral Sensitivity during the Evolution of Therapeutic Resistance in Ewing’s Sarcoma. iScience. 2020. PMC7334607.
Scott, J. G., Sedor, G., Scarborough, J. A., Kattan, M. W., Peacock, J., Grass, G. D., Mellon, E.A., Thapa, R., Schell, M., Waller, A., Poppen, S., Andl, G., Teer, J.K., Eschrich, S.A., Dilling, T.J., Dalton W.S., Harrison, L.B., Fox, T., Torres-Roca, J. F. (2020). Personalizing Radiotherapy Prescription Dose Using Genomic Markers of Radiosensitivity and Normal Tissue Toxicity in NSCLC. Journal of Thoracic Oncology. 2020. PMID: 33301984
Scarborough J.A., Paul J.R., Spencer J.V., “Evolution of the ability to modulate host chemokine networks via gene duplication in human cytomegalovirus (HCMV).” Infection, Genetics, and Evolution. July 2017. PMID: 28315475
Oral Presentations
Scarborough J.A., McClure E., Hitomi M., Anderson P., Scott J., “Exploiting Convergent Evolution to Extract States of Collateral Sensitivity in Ewing Sarcoma” (2019). Oral Presentation. Innovators in AYA Cancer; Case Comprehensive Cancer Center; Cleveland, OH
Scarborough J.A., Dhawan A., Eschrich S., Torres-Roca J., Scott J.G., “The extraction and validation of the Cisplatin Sensitivity Signature (CisSig)” (2021). Oral Presentation. Case Comprehensive Cancer Center Annual Retreat; Cleveland, OH
Scarborough J.A., Dhawan A., Eschrich S., Torres-Roca J., Scott J.G., “The extraction and validation of the Cisplatin Sensitivity Signature (CisSig)” (2022). Oral Presentation. Wellcome Connecting Sciences Evolutionary Systems Biology 2022 Conference; Virtual
Poster Presentations
Scarborough J.A., Loddenkemper T., Bosl W., “Nonlinear Analysis for Detection and Classification of Benign Childhood Epilepsy with Centrotemporal Spikes (BECTS)” (2017). Poster Presentation. American Clinical Neurophysiology Society Annual Meeting and Conference; Phoenix, AZ.
Scarborough J.A., Spencer J.V., Paul J., “Virus-Host Co-evolution: Determining the Origin of Human Cytomegalovirus US27 and US28” (2016). Poster Presentation. Creative Activity and Research Day; University of San Francisco, San Francisco, CA.
Scarborough, J.A., Dhawan, A., Scott, J., “Generating Gene Expression Signatures Predictive of Therapeutic Response in Lung Adenocarcinoma” (2018). Poster presentation. Cleveland Clinic Foundation Lerner Research Day; Cleveland, OH.
Scarborough, J.A., Dhawan, A., Scott, J., “Generating Gene Expression Signatures Predictive of Therapeutic Response in Lung Adenocarcinoma” (2018). Poster presentation. Case Western Reserve University Lepow Research Day; Cleveland, OH.
Scarborough, J.A., Dhawan, A., Scott, J., “A Novel Method for Extracting Gene Signatures Predictive of Chemotherapeutic Response” (2019). Poster presentation. Case Western Reserve University Lepow Research Day; Cleveland, OH
Scarborough, J.A., McClure, E., Sedor, G., Hitomi, M., Scott, JG. Identifying States of Collateral Sensitivity During the Evolution of Therapy Resistance in Ewing’s Sarcoma. (2019) Poster Presentation. Innovators in AYA Cancer Symposium. Cleveland, OH.
Scarborough, J.A., Dhawan A., Scott, J.G. Deriving Robust Gene Signatures Predictive of Chemotherapeutic Response. (2019) Poster Presentation. Case Western Reserve University Biomedical Graduate Student Symposium. Cleveland, OH.
Scarborough, J.A, Dhawan, A., Scott, J., Deriving Robust Gene Signatures Predictive of Chemotherapeutic Response (2020). Poster presentation. American Association for Cancer Research 2020 Virtual Annual Meeting II. Virtual Meeting due to COVID-19.
Scarborough, J.A., Tom, M., Scott, J.G. Revisiting a Null Hypothesis: Exploring the parameters of oligometastasis treatment (2020) Poster Presentation. Case Western Reserve University Biomedical Graduate Student Symposium. Cleveland, OH. *Best Poster Award
Scarborough, J.A., Tom, M., Kattan, M., Scott, J.G. Revisiting a Null Hypothesis: Exploring the parameters of oligometastasis treatment (2021) Poster Presentation. Case Western Reserve University Lepow Day. Cleveland, OH.
Scarborough J.A., Dhawan A., Eschrich S., Torres-Roca J., Scott J.G., “The extraction and validation of the Cisplatin Sensitivity Signature (CisSig)” (2021). Poster Presentation. Case Western Reserve University Biomedical Graduate Student Symposium; Cleveland, OH * Best Poster Award
Scarborough, J.A., Nair, M., Scott, J.G., Mian, O., “Recursive partitioning analysis to define novel prognostic groups in bladder cancer patients undergoing curative intent tri-modality therapy” (2022). Poster Presentation. AAP/ASCI/APSA Joint Meeting 2022; Chicago, IL
Nair, M., Scarborough, J.A., Gupta, S., Gilligan, T. D., Nizam, A., Ornstein, M. C., ... & Mian, O. Y. (2023). A single institution experience of multimodality radiation therapy for muscle-invasive bladder cancer.